The combination of field-directed therapy and cryotherapy reportedly is more effective than cryotherapy alone
Warts can usually be treated with two 15- to 30-second freeze-thaw cycles, depending on the thickness
Experts agree that cryotherapy can be helpful in removing genital warts
In some studies, cryotherapy removed warts in up to 90 out of 100 cases
warts may grow back
More than one treatment may be needed
The removal of genital warts may not cure a human papillomavirus (HPV) infection
Vascular malformations of blue rubber bleb nevus syndrome have been treated with a single 10-second freeze
Cysts and tumors
One 10-second freeze-thaw cycle with a 1-mm margin can be used to treat acne cysts
Other lesions One 15- to 30-second freeze-thaw cycle with a 1-mm margin can be used to treat keloids
Cryotherapy of keloids can be done
Rhinophyma can be treated with two 30-second freeze-thaw cycles of the entire nose at 4-week intervals
Most nonmelanoma skin cancers, such as squamous cell carcinomas and basal cell carcinomas, should be treated by excision with sufficient margins, by Mohs surgery, or with radiation
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